Enhanced diagnostic confidence in Neuro-oncology
Establishing the diagnosis of a brain tumor is not always straightforward. MRI is the gold standard but not reliable enough for tumor follow up.1 The presence of contrast enhancement can confuse the diagnosis of malignant brain tumors, and therefore differentiating low- from high-grade gliomas can prove to be a challenge for radiologists. With three out of five radiologists finding brain tumor diagnosis “challenging” to “very challenging,” it’s evident that this is an area of unmet need; there is also a vital demand for methods that can detect response to therapy at early follow-up times.2
Philips 3D APT (Amide Proton Transfer) is a unique, contrast-free, brain MR imaging method, designed to help radiologists differentiate between low-grade and high-grade gliomas. This technology works by using the presence of endogenous cellular proteins to produce an MR signal that directly correlates with cell proliferation, a marker of tumor activity.
1 Neurology. 2002 Sep 24;59(6):947-9.
2 Cancer Manag Res. 2014; 6: 149–170.