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With ×Count, you can take advantage of quantification even on investigations that involve dynamic, short-lived tracers.

Supporting stability across count rates

The Ingenuity TF PET/CT uses high-throughput acquisition hardware that expands its count-rate capabilities, with improved linearity at high count rates. Thanks to ×Count, the system is stable across count rates (low to high), so you can perform dynamic imaging with a wide range of tracers including (82Rb) Rubidium chloride.

The TOF technology available on the Ingenuity TF PET/CT provides improved signal-to-noise ratio in the reconstructed images in addition to better count rate performance and better randoms rejection over non-TOF PET.

Dynamic imaging with a wide range of tracers

Myocardial perfusion scan using (82Rb) Rubidium chloride

Image courtesy of the University Hospital Cleveland, USA

C-11	N-13	O-14	O-15	F-18	Na-22
K-38	Ti-45	Mn-52m	Cu-60	Cu-61	Cu-62
Zn-62	Cu-64	Ga-66	Ga-68	Ge-68	Br-75
Br-76	Br-77	Rb-82	Y-86	Tc-94m	I-124

xCount in action - performance evaluation*

Parameters:

Timing
Energy resolution
Dead time
Linearity of image
activity concentration

Results:

NEMU NU peak true countrate: 365 kcps at 35 kBq/mL
Range of activity at which the NECR was above 90% of its peak value spanned 368 MBq (from 241 to 609 MBq)

Conclusion:

System performance is suitable for application in high-count-rate PET application

*Kolthammer J., et. al. Performance evaluation of the Ingenuity TF PET/CT scanner with a focus on high count-rate conditions.
Physics in Medicine and Biology. 2014;59:3843-59

This system helps us work with a variety of tracers in a cost-effective way. A lot of my brain studies use [18F]-FDG, but other radiopharmaceuticals can shed light on different neurological conditions.”

Prof. Dr. Maria Santiago Ribeiro

Head of Nuclear Medicine, Hôpital Bretonneau, Centre Hospitalier Régional Universitaire de Tours, France

Downloads

Want to learn more about how research and clinical routines can benefit from xCount and the entire xPand5 technology suite?

Download the brochure (PDF)

To find out more and gain answers to your open questions, please get in touch.

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